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KMID : 0895820200300020037
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Journal of Oriental Rehabilitation Medicine
2020 Volume.30 No. 2 p.37 ~ p.46
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Effects of Dioscoreae Rhizoma on Excercise Practice Ability and Blood Fatigue Variable Factor
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Park Na-Ri
Lee Yun-Jin
Lee Eun-Byeol
Yang Doo-Hwa
Woo Chang-Hoon
An Hee-Duk
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Abstract
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Objectives: In this study, we analyzed the effect of Dioscoreae Rhizoma on exercise practice ability and blood fatigue variable factor in the forced swimming test.
Methods: Male mice were divided into four group. Mice were administrated with saline, Discorae Rhizoma extracted by water (DRW), Discorae Rhizoma extracted by 30% ethanol (DRE), red ginseng (RG), orally once per day, for 1 week. Exercise performance was evaluated by exhaustive swimming time and weights. Glycogen contents of liver and soleus muscle were measured at the end of the experiment. In addition, the biochemical parameters such as asparate aminotransferase (AST), alanine aminotransferase (ALT), blood urea nitrogen, creatine, lactate dehydrogenase (LDH), ammonia, triglycerides (TG), total cholesterol (TC) and free fatty acid (FFA) were analyzed.
Results: Both DRW and DRE showed an improvement of swimming endurance compared with control group. Levels of ALT, ammonia, TG, TC and FFA were significantly decreased in both DRW and DRE compared with control group. Levels of AST, Creatine were significantly reduced in DRE group compared with control group. Moreover LDH showed only a tendency to increase in the DRW and DRE groups.
Conclusions: In summary, the present study showed that Dioscoreae Rhizoma improved in physical fatigue and exercise practice ability and DRE improved the superior than those of DRW.
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KEYWORD
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Dioscoreae Rhizoma, Exercise practice ability, Forced swimming test, Fatigue
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